Synthetic vascular graft - Dacron

29/11/2011 00:32

Also known as Polyethylene Terephthalate, Dacron comes into two forms which are woven and knitted form.

 

Woven Dacron

  • low porosity (<500ml/ cm2/ min),
  • no need pre-clotting
  • strong
  • stiff (non-stretchable
  • poor handling
  • frays at cut edges

Knitted Dacron

  • high porosity (1200-1900 ml/ cm2/ min)
  • need pre-clotting
  • less durable
  • dilate
  • softer
  • better handling
  • do not fraying

Ways of modification of Dacron for better vascular graft

  • Cramping - accordion pleats and is useful as it helps to improve handling and elasticity.
  • Impregnation - by impregnating biodegradable substances eg: fibrin, collagen to fill the interstices of the fabric and reduce blood loss and negate the need of pre-clot. 
  • Velour - applying additional loops of yarns which are piled perpendicularly to the surface-velour

A synthetic polymer polyester terephthalate (PET), also known as Dacron is mostly recognized because it is found to be biocompatible, flexible, resilient, durable and resistant to biodegradation and sterilization.